000			02048cam a22003135a 4500
001			017626671
003			OSt
005			20171226105758.0
008			151116t2016 sz frbf 001 0 eng d
020			_a9783319053912
040			_aStDuBDS _beng _cStDuBDS _dEG-ScBUE
082	0	4	_a615.19 _bDRU _222
245	0	0	_aDrug discovery and evaluation : _bpharmacological assays / _cedited by Franz J. Hock.
250			_a4th ed.
260			_aCham : _bSpringer International Publishing, _cc.2016.
300			_a4 v. : _bill. ; _c24 cm.
490	0		_aSpringer reference
504			_aIncludes bibliographical references and index.
505			_av. 1. -- v. 2. -- v. 3.
520			_aThe 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc
650		7	_aPharmacology, Experimental. _2BUEsh
650		7	_aDrugs _xDesign. _2BUEsh _930136
650		7	_aDrugs _xTesting. _2BUEsh
651			_2BUEsh
653			_bPPhrm _cOctober2017 _cDecember2017
700	1		_aHock, Franz J., _eeditor.
776	0	8	_iPrint version : _z9783319053912
942			_2ddc
999			_c25528 _d25500