MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02208cam a22002895a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
017472678 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
Uk |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20181031123521.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150717s2016 enka frb 001 0 eng d |
| 015 ## - NATIONAL BIBLIOGRAPHY NUMBER |
|---|
| National bibliography number |
GBB5A6276 |
| Source |
bnb |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| Cancelled/invalid ISBN |
9780081000984 (hbk.) |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
StDuBDS |
| Language of cataloging |
eng |
| Transcribing agency |
StDuBDS |
| Modifying agency |
Uk |
| -- |
EG-ScBUE |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.19 |
| Item number |
HON |
| Edition number |
22 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hongmao, Sun. |
| 9 (RLIN) |
41857 |
| 245 12 - TITLE STATEMENT |
|---|
| Title |
A practical guide to rational drug design / |
| Statement of responsibility, etc |
Sun Hongmao. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Cambridge ; |
| -- |
Waltham, MA : |
| Name of publisher, distributor, etc |
Woodhead Publishing / Elsevier, |
| Date of publication, distribution, etc |
c.2016. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
275 p. : |
| Other physical details |
ill. (col.) ; |
| Dimensions |
24 cm. |
| 490 0# - Series Statement |
|---|
| Series statement |
Woodhead Publishing series in biomedicine ; |
| Volume/sequential designation |
no. 81 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Title |
PART I Rational Drug Design 1. Structure of the target is available 2. Structure of the target is unavailable 3. Virtual screening (VS) |
| -- |
PART II Chemoinformatics 1. QSAR modeling 2. Processing HTS results 3. Delivering modeling results |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors' active compounds or from natural ligands of the targets; how to springboard from competitors' SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Drugs |
| General subdivision |
Design. |
| Source of heading or term |
BUEsh |
| 9 (RLIN) |
30136 |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Source of heading or term |
BUEsh |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Resource For college |
Pharmacy |
| -- |
Generalities |
| Arrived date list |
October2018 |
| 655 ## - INDEX TERM--GENRE/FORM |
|---|
| Form subdivision |
Reading book |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Print version: |
| International Standard Book Number |
9780081000984 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |