The organic chemistry of drug design and drug action /

Silverman, Richard B.

The organic chemistry of drug design and drug action / Richard B. Silverman, Mark W. Holladay. - 3rd ed. - San Diego : Academic Press / Elsevier, c.2014. - xviii, 517 p. : ill. ; 29 cm.

Index : p. 507-517. Includes appendix.

Includes bibliographic references.

Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.

9780123820303 (alk. paper)


Pharmaceutical chemistry.
Bioorganic chemistry.
Molecular pharmacology.
Drugs--Design.





615.19 / SIL